Empowering you to be your best diagnostician

Get a differential diagnosis with the diseases you are expecting AND unfamiliar diseases that should be considered for your patient.
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Useful findings

Get prompted with useful findings, driven by the evolving differential diagnosis. Diagnosis is iterative, far better than a one-shot Web search. Even comment on pertinent negative findings. Or click the magnifying glass in the software to use our new improved search.

Loss of heterozygosity

Use your microarray results to consider genes in regions of loss of heterozygosity. Then get suggestions of other useful clinical findings or tests to make the diagnosis or guide testing.

Mobile device support

Now runs on mobile devices as well as computers, so you can use it whenever you need it. There is no app to install. Just navigate to the software as you would on a personal computer.

Sophisticated time model

Use onset and disappearance age of findings, and speed of emergence of your patient's disease to distinguish among diseases with similar findings but different time course.

Use test results, even genomes

Include all test results for your patient, including results from genomic testing. In the Genome-Phenome version, you can even get help with gene discovery, and this now supports analysis beyond the trio.

Prognosis table

Offer your patient and referring physicians a highly-rated table of what to expect over time for each disease you diagnose.

Sophisticated family history model

Combines a simple interface for family history with a very sophisticated model under the hood. As an example, X-linked diseases are considered as a spectrum between dominant and recessive, specified for each disease in the database but displayed in a way that is simple for the user.

Beyond the trio genomic analysis

If you have more genomic data than just a trio, such as siblings, cousins, or even unrelated individuals, the Genome-Phenome Analyzer can use the information and narrow down the analysis, even for gene discovery.

Lots of links to articles and pictures

When a disease or finding is active, explore the Tips links for explanations, calculators, articles and photos. Read our roundup of different types of skin lines to brush up on dermatomal vs. Blaschko versus Langer lines of cleavage. Or get a head circumference percentile.

ABOUT US

Designed by doctors for doctors

Designed by doctors for doctors. We know you rarely need help with diagnosis in your specialty, but with the extraordinary growth of medical knowledge, you may value prompts about unfamiliar candidate diseases in adjacent specialties. That is why we have built SimulConsult as a single model across all specialties, so that the differential diagnosis includes both the diseases you are expecting and also unfamiliar diseases that should be considered for your patient.

User Stories

I use it all the time
I use SimulConsult at several points. I typically use it as I review the notes or referral, to prepare myself for the patient meeting and exam. Sometimes I use it after seeing a patient as I think about my assessment. I use it to help me interpret the results from exome and genome testing in the clinical context. Recently, I have been finding that if I submit the Patient Summary to insurance when I order genetic testing, they consider it proof of my thoroughness and approve reimbursement with no further documentation.
I felt like I had ‘Superpowers’
I was called in to consult on a neurology in-patient after several days without a diagnosis. No rheumatology diagnosis seemed obvious and searching the Web got me nowhere. I put the patient’s findings into SimulConsult. It suggested a disease with which I was unfamiliar. Using the resources provided I became convinced we should consider Morvan Syndrome in our differential diagnosis. The software suggested the relevant test. I ordered it and the result was positive. I felt like I had superpowers to diagnose a disease I didn’t know beforehand.
Your update to a disease helped me diagnose a patient
When the new results came out that the creatine transporter deficiency disease was orders of magnitude more common than had been previously been appreciated, and when SimulConsult then updated the incidence in the database, something magical happened. I was checking on a patient who was on a lengthy diagnostic odyssey. Creatine transporter deficiency appeared prominently for the first time in the differential diagnosis, I ordered the recommended test and sure enough, we had a diagnosis.
Would have saved nearly $200,000
Eventually we reached a diagnosis of ALS, but because it is a diagnosis of exclusion, a huge number of tests were ordered at multiple centers. All it takes is 3-4 pertinent findings in SimulConsult and the answer is clear. If the family had learned the diagnosis earlier they would have had time to record the patient’s voice. Beyond saving money, the quality of life for the last couple of years would have been much higher.

Interface Highlights

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